Winery: St. James Winery in St. James, Missouri

Thousands of people drive by St. James Winery just off Interstate 44 in St. James, Missouri, each day. Stop in the tasting room to sip wines like the Estate Norton, a gold winner at the 2018 Pacific Rim International Wine Competition, and Vignoles, a two-time Governor’s Cup winner at the Missouri Wine Competition. (Photo courtesy of St. James Winery)

St. James Winery, stjameswinery.com

» Runner-Up: Leaky Roof Meadery in Buffalo, Missouri, leakyroofmeadery.com