Vegetarian: Main Squeeze

When Leigh Lockhart opened Main Squeeze in Columbia in 1997, she was serving all-natural juices and smoothies inside Lakota Coffee Co. She opened her own storefront a year later, and Main Squeeze has been a favorite for vegetarian fare ever since. Try the Ruby, a play on a Reuben loaded with tempeh, Swiss cheese, onion, sauerkraut, tomato, lettuce and Russian dressing. (Photo by Aaron Ottis)

Main Squeeze, main-squeeze.com

» Runner-Up: Nourish Café & Market, nourishcafemarket.com